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Inhibition of ornithine decarboxylase 1 facilitates pegylated arginase treatment in lung adenocarcinoma xenograft models

Arginine depletion has shown anticancer effects among arginine auxotrophic cancers. An anti-proliferative effect of pegylated arginase (BCT-100) has been shown in acute myeloid leukaemia, hepatocellular carcinoma and mesothelioma. The aim of the present study was to evaluate the effect of BCT-100 in...

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Опубликовано в: :Oncol Rep
Главные авторы: Lam, Sze-Kwan, Pong U, Kin, Li, Yuan-Yuan, Xu, Shi, Cheng, Paul Ning-Man, Ho, James Chung-Man
Формат: Artigo
Язык:Inglês
Опубликовано: D.A. Spandidos 2018
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC6111542/
https://ncbi.nlm.nih.gov/pubmed/30066894
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/or.2018.6598
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