Multiplexed CRISPR/Cas9 Targeting of Genes Implicated in Retinal Regeneration and Degeneration

Thousands of genes have been implicated in retinal regeneration, but only a few have been shown to impact the regenerative capacity of Müller glia—an adult retinal stem cell with untapped therapeutic potential. Similarly, among nearly 300 genetic loci associated with human retinal disease, the major...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Front Cell Dev Biol
Prif Awduron: Unal Eroglu, Arife, Mulligan, Timothy S., Zhang, Liyun, White, David T., Sengupta, Sumitra, Nie, Cathy, Lu, Noela Y., Qian, Jiang, Xu, Lisha, Pei, Wuhong, Burgess, Shawn M., Saxena, Meera T., Mumm, Jeff S.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Frontiers Media S.A. 2018
Pynciau:
Cell and Developmental Biology
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC6111214/
https://ncbi.nlm.nih.gov/pubmed/30186835
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fcell.2018.00088
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