Multiplexed CRISPR/Cas9 Targeting of Genes Implicated in Retinal Regeneration and Degeneration

Thousands of genes have been implicated in retinal regeneration, but only a few have been shown to impact the regenerative capacity of Müller glia—an adult retinal stem cell with untapped therapeutic potential. Similarly, among nearly 300 genetic loci associated with human retinal disease, the major...

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Bibliografiset tiedot
Julkaisussa:Front Cell Dev Biol
Päätekijät: Unal Eroglu, Arife, Mulligan, Timothy S., Zhang, Liyun, White, David T., Sengupta, Sumitra, Nie, Cathy, Lu, Noela Y., Qian, Jiang, Xu, Lisha, Pei, Wuhong, Burgess, Shawn M., Saxena, Meera T., Mumm, Jeff S.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Frontiers Media S.A. 2018
Aiheet:
Cell and Developmental Biology
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC6111214/
https://ncbi.nlm.nih.gov/pubmed/30186835
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fcell.2018.00088
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