Oxygen Limitation Enhances the Antimicrobial Activity of Fosfomycin in Pseudomonas aeruginosa Following Overexpression of glpT Which Encodes Glycerol-3-Phosphate/Fosfomycin Symporter

Fosfomycin is resurfacing as a “last resort drug” to treat infections caused by multidrug resistant pathogens. This drug has a remarkable benefit in that its activity increases under oxygen-limited conditions unlike other commonly used antimicrobials such as β-lactams, fluoroquinolones and aminoglyc...

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Bibliografske podrobnosti
izdano v:Front Microbiol
Main Authors: Hirakawa, Hidetada, Kurabayashi, Kumiko, Tanimoto, Koichi, Tomita, Haruyoshi
Format: Artigo
Jezik:Inglês
Izdano: Frontiers Media S.A. 2018
Teme:
Microbiology
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC6110920/
https://ncbi.nlm.nih.gov/pubmed/30186264
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fmicb.2018.01950
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