Metabolic Reprogramming of Clostridioides difficile During the Stationary Phase With the Induction of Toxin Production

The obligate anaerobe, spore forming bacterium Clostridioides difficile (formerly Clostridium difficile) causes nosocomial and community acquired diarrhea often associated with antibiotic therapy. Major virulence factors of the bacterium are the two large clostridial toxins TcdA and TcdB. The produc...

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Dettagli Bibliografici
Pubblicato in:Front Microbiol
Autori principali: Hofmann, Julia D., Otto, Andreas, Berges, Mareike, Biedendieck, Rebekka, Michel, Annika-Marisa, Becher, Dörte, Jahn, Dieter, Neumann-Schaal, Meina
Natura: Artigo
Lingua:Inglês
Pubblicazione: Frontiers Media S.A. 2018
Soggetti:
Microbiology
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6110889/
https://ncbi.nlm.nih.gov/pubmed/30186274
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fmicb.2018.01970
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