Metabolic Reprogramming of Clostridioides difficile During the Stationary Phase With the Induction of Toxin Production

The obligate anaerobe, spore forming bacterium Clostridioides difficile (formerly Clostridium difficile) causes nosocomial and community acquired diarrhea often associated with antibiotic therapy. Major virulence factors of the bacterium are the two large clostridial toxins TcdA and TcdB. The produc...

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Publicat a:Front Microbiol
Autors principals: Hofmann, Julia D., Otto, Andreas, Berges, Mareike, Biedendieck, Rebekka, Michel, Annika-Marisa, Becher, Dörte, Jahn, Dieter, Neumann-Schaal, Meina
Format: Artigo
Idioma:Inglês
Publicat: Frontiers Media S.A. 2018
Matèries:
Microbiology
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6110889/
https://ncbi.nlm.nih.gov/pubmed/30186274
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fmicb.2018.01970
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