Coumarin Reduces Virulence and Biofilm Formation in Pseudomonas aeruginosa by Affecting Quorum Sensing, Type III Secretion and C-di-GMP Levels

As one of the major pathogens in wound infections, Pseudomonas aeruginosa produces several virulence factors and forms biofilms; these processes are under the regulation of various quorum sensing (QS) systems. Therefore, QS has been regarded as a promising target to treat P. aeruginosa infections. I...

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Detalhes bibliográficos
Publicado no:Front Microbiol
Main Authors: Zhang, Yunhui, Sass, Andrea, Van Acker, Heleen, Wille, Jasper, Verhasselt, Bruno, Van Nieuwerburgh, Filip, Kaever, Volkhard, Crabbé, Aurélie, Coenye, Tom
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2018
Assuntos:
Microbiology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6110822/
https://ncbi.nlm.nih.gov/pubmed/30186266
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fmicb.2018.01952
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