Blood-Cerebrospinal Fluid Barrier Gradients in Mild Cognitive Impairment and Alzheimer's Disease: Relationship to Inflammatory Cytokines and Chemokines

Background: The pathophysiology underlying altered blood-cerebrospinal fluid barrier (BCSFB) function in Alzheimer's disease (AD) is unknown but may relate to endothelial cell activation and cytokine mediated inflammation. Methods: Cerebrospinal fluid (CSF) and peripheral blood were concurrentl...

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Pubblicato in:Front Aging Neurosci
Autori principali: Ott, Brian R., Jones, Richard N., Daiello, Lori A., de la Monte, Suzanne M., Stopa, Edward G., Johanson, Conrad E., Denby, Charles, Grammas, Paula
Natura: Artigo
Lingua:Inglês
Pubblicazione: Frontiers Media S.A. 2018
Soggetti:
Neuroscience
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6110816/
https://ncbi.nlm.nih.gov/pubmed/30186149
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fnagi.2018.00245
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