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Optogenetic induction of the schizophrenia-related endophenotype of ventral hippocampal hyperactivity causes rodent correlates of positive and cognitive symptoms

Pathological over-activity of the CA1 subfield of the human anterior hippocampus has been identified as a potential predictive marker for transition from a prodromal state to overt schizophrenia. Psychosis, in turn, is associated with elevated activity in the anterior subiculum, the hippocampal outp...

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Bibliografiske detaljer
Udgivet i:Sci Rep
Main Authors: Wolff, Amy R., Bygrave, Alexei M., Sanderson, David J., Boyden, Edward S., Bannerman, David M., Kullmann, Dimitri M., Kätzel, Dennis
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group UK 2018
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6110795/
https://ncbi.nlm.nih.gov/pubmed/30150758
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-31163-5
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