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Human notochordal cell transcriptome unveils potential regulators of cell function in the developing intervertebral disc

The adult nucleus pulposus originates from the embryonic notochord, but loss of notochordal cells with skeletal maturity in humans is thought to contribute to the onset of intervertebral disc degeneration. Thus, defining the phenotype of human embryonic/fetal notochordal cells is essential for under...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Rodrigues-Pinto, Ricardo, Ward, Lizzy, Humphreys, Matthew, Zeef, Leo A. H., Berry, Andrew, Hanley, Karen Piper, Hanley, Neil, Richardson, Stephen M., Hoyland, Judith A.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6110784/
https://ncbi.nlm.nih.gov/pubmed/30150762
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-31172-4
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