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HIV-1 intron-containing RNA expression induces innate immune activation and T cell dysfunction
Low levels of type I interferon (IFN-I) are thought to be a driving force for immune activation and T-cell exhaustion in HIV-1 infected individuals on combination antiretroviral therapy (cART), though the causative mechanisms for persistent IFN-I signaling have remained unclear. Here, we show Rev–CR...
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| Publicado no: | Nat Commun |
|---|---|
| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group UK
2018
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6110775/ https://ncbi.nlm.nih.gov/pubmed/30150664 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-018-05899-7 |
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