Endogenous Galectin-9 Suppresses Apoptosis in Human Rheumatoid Arthritis Synovial Fibroblasts

Galectin-9 (Gal9) has been postulated to have anti-inflammatory properties based on the ability of exogenous Gal9 to induce apoptosis in synovial fibroblasts in animal models of rheumatoid arthritis (RA). Here we aimed to assess the potential role of endogenous Galectins, including Gal9, in the infl...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Pearson, Mark J., Bik, Magdalena A., Ospelt, Caroline, Naylor, Amy J., Wehmeyer, Corinna, Jones, Simon W., Buckley, Christopher D., Gay, Steffen, Filer, Andrew, Lord, Janet M.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2018
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6110759/
https://ncbi.nlm.nih.gov/pubmed/30150656
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-31173-3
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