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Mechanical interactions among followers determine the emergence of leaders in migrating epithelial cell collectives
Regulating the emergence of leaders is a central aspect of collective cell migration, but the underlying mechanisms remain ambiguous. Here we show that the selective emergence of leader cells at the epithelial wound-margin depends on the dynamics of the follower cells and is spatially limited by the...
Kaydedildi:
| Yayımlandı: | Nat Commun |
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| Asıl Yazarlar: | , , , , , |
| Materyal Türü: | Artigo |
| Dil: | Inglês |
| Baskı/Yayın Bilgisi: |
Nature Publishing Group UK
2018
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| Konular: | |
| Online Erişim: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6110746/ https://ncbi.nlm.nih.gov/pubmed/30150695 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-018-05927-6 |
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