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Hemodynamic and Histopathologic Benefits of Early Treatment with Macitentan in a Rat Model of Pulmonary Arterial Hypertension

BACKGROUND AND OBJECTIVES: Macitentan (MAC) reduces morbidity and mortality among advanced-stage pulmonary arterial hypertension (PAH) patients. However, data regarding the histopathologic and hemodynamic benefits of MAC treatment at an early stage of PAH is lacking. METHODS: One week after monocrot...

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Vydáno v:Korean Circ J
Hlavní autoři: Kim, Kyung-Hee, Kim, Hyung-Kwan, Chan, Stephen Y., Kim, Yong-Jin, Sohn, Dae-Won
Médium: Artigo
Jazyk:Inglês
Vydáno: The Korean Society of Cardiology 2018
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6110709/
https://ncbi.nlm.nih.gov/pubmed/30088353
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4070/kcj.2017.0394
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