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IGF1/IGF1R and microRNA let-7e down-regulate each other and modulate proliferation and migration of colorectal cancer cells

MicroRNA let-7 has been reported to be down-regulated in several human cancers and is now characterized as a tumor suppressor. IGF1R is over-expressed in many cancers and IGF1/IGF1R pathway is attractive target for anticancer therapy. However, the crosstalk between let-7 and IGF1/IGF1R are largely u...

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Vydáno v:Cell Cycle
Hlavní autoři: Li, Zhenjun, Pan, Weihuo, Shen, Yi, Chen, Zhiliang, Zhang, Lihua, Zhang, Yuping, Luo, Quan, Ying, Xiaojiang
Médium: Artigo
Jazyk:Inglês
Vydáno: Taylor & Francis 2018
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6110595/
https://ncbi.nlm.nih.gov/pubmed/29886785
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/15384101.2018.1469873
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