Cargando...
An investigational RNAi therapeutic targeting antithrombin for the treatment of hemophilia A and B
Fitusiran is an RNA interference therapeutic that targets antithrombin (AT) in the liver and interferes with AT translation by binding and degrading messenger RNA-AT, thereby silencing AT gene expression and preventing AT synthesis. In both preclinical and clinical studies, AT knockdown results in d...
Guardado en:
| Publicado en: | J Blood Med |
|---|---|
| Autores principales: | , |
| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
Dove Medical Press
2018
|
| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6110283/ https://ncbi.nlm.nih.gov/pubmed/30174468 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/JBM.S159297 |
| Etiquetas: |
Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!
|