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Prolonging pulse duration in ultrasound-mediated gene delivery lowers acoustic pressure threshold for efficient gene transfer to cells and small animals

While ultrasound-mediated gene delivery (UMGD) has been accomplished using high peak negative pressures (PNPs) of 2 MPa or above, emerging research showed that this may not be a requirement for microbubble (MB) cavitation. Thus, we investigated lower-pressure conditions close to the MB inertial cavi...

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Bibliografski detalji
Izdano u:J Control Release
Glavni autori: Tran, Dominic M., Harrang, James, Song, Shuxian, Chen, Jeremy, Smith, Bryn M., Miao, Carol H.
Format: Artigo
Jezik:Inglês
Izdano: 2018
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6110264/
https://ncbi.nlm.nih.gov/pubmed/29702143
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jconrel.2018.04.012
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