A Genome-Wide Scan for MicroRNA-Related Genetic Variants Associated With Primary Open-Angle Glaucoma

PURPOSE: To identify microRNAs (miRNAs) involved in primary open-angle glaucoma (POAG), using genetic data. MiRNAs are small noncoding RNAs that posttranscriptionally regulate gene expression. Genetic variants in miRNAs or miRNA-binding sites within gene 3′-untranslated regions (3′UTRs) are expected...

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Detalhes bibliográficos
Publicado no:Invest Ophthalmol Vis Sci
Main Authors: Ghanbari, Mohsen, Iglesias, Adriana I., Springelkamp, Henriët, van Duijn, Cornelia M., Ikram, M. Arfan, Dehghan, Abbas, Erkeland, Stefan J., Klaver, Caroline C. W., Meester-Smoor, Magda A.
Formato: Artigo
Idioma:Inglês
Publicado em: The Association for Research in Vision and Ophthalmology 2017
Assuntos:
Genetics
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6110129/
https://ncbi.nlm.nih.gov/pubmed/29049738
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1167/iovs.17-22410
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