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Overcoming P-Glycoprotein-Mediated Multidrug Resistance in Colorectal Cancer: Potential Reversal Agents among Herbal Medicines

OBJECTIVES: Multidrug resistance (MDR) is the major reason for the failure of chemotherapy in colorectal cancer (CRC), and the primary determinant of MDR in CRC patients is active drug efflux owing to overexpression of P-glycoprotein (P-gp) in cancer tissues. Despite research efforts to overcome P-g...

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Publicado en:Evid Based Complement Alternat Med
Autores principales: Lee, Gayoung, Joung, Jin-Yong, Cho, Jung-Hyo, Son, Chang-Gue, Lee, Namhun
Formato: Artigo
Lenguaje:Inglês
Publicado: Hindawi 2018
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC6109522/
https://ncbi.nlm.nih.gov/pubmed/30158992
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2018/3412074
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