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Polymorphisms in the Toll-like receptor 3 (TLR3) gene are associated with the natural course of hepatitis B virus infection in Caucasian population

Innate immunity can induce spontaneous hepatitis B surface antigen (HBsAg) seroclearance (SC) of hepatitis B virus (HBV) infection or transition towards an inactive carrier state. Toll-like receptor (TLR) 3 signalling has been linked to these processes. Alterations in the TLR3 gene might impair immu...

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Detalles Bibliográficos
Publicado en:Sci Rep
Main Authors: Fischer, Janett, Koukoulioti, Eleni, Schott, Eckart, Fülöp, Balazs, Heyne, Renate, Berg, Thomas, van Bömmel, Florian
Formato: Artigo
Idioma:Inglês
Publicado: Nature Publishing Group UK 2018
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6109130/
https://ncbi.nlm.nih.gov/pubmed/30143709
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-31065-6
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