Neurofilament light interaction with GluN1 modulates neurotransmission and schizophrenia-associated behaviors

Neurofilament (NFL) proteins have recently been found to play unique roles in synapses. NFL is known to interact with the GluN1 subunit of N-methyl-d-aspartic acid (NMDAR) and be reduced in schizophrenia though functional consequences are unknown. Here we investigated whether the interaction of NFL...

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Publicado no:Transl Psychiatry
Main Authors: Yuan, Aidong, Veeranna, Sershen, Henry, Basavarajappa, Balapal S., Smiley, John F., Hashim, Audrey, Bleiwas, Cynthia, Berg, Martin, Guifoyle, David N., Subbanna, Shivakumar, Darji, Sandipkumar, Kumar, Asok, Rao, Mala V., Wilson, Donald A., Julien, Jean-Pierre, Javitt, Daniel C., Nixon, Ralph A.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2018
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6109052/
https://ncbi.nlm.nih.gov/pubmed/30143609
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41398-018-0194-7
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