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Targeted inhibition of Axl receptor tyrosine kinase ameliorates anti-GBM-induced lupus-like nephritis

Glomerulonephritis (GN) is a typical lesion in autoantibody and immune complex disorders, including SLE. Because the Gas6/Axl pathway has been implicated in the pathogenesis of many types of GN, targeting this pathway might ameliorate GN. Consequently, we have studied the efficacy and mechanism of R...

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Publicat a:J Autoimmun
Autors principals: Zhen, Yuxuan, Lee, Iris J., Finkelman, Fred D., Shao, Wen-Hai
Format: Artigo
Idioma:Inglês
Publicat: 2018
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6108947/
https://ncbi.nlm.nih.gov/pubmed/29895432
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jaut.2018.06.001
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