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Physiologically Based Pharmacokinetic (PBPK) Modeling of the Bisphenols BPA, BPS, BPF, and BPAF with New Experimental Metabolic Parameters: Comparing the Pharmacokinetic Behavior of BPA with Its Substitutes

BACKGROUND: The endocrine disrupting chemical bisphenol A (BPA) has been facing stricter regulations in recent years. BPA analogs, such as the bisphenols S, F, and AF (BPS, BPF, and BPAF) are increasingly used as replacement chemicals, although they were found to exert estrogenic effects similar to...

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Detalles Bibliográficos
Publicado en:Environ Health Perspect
Main Authors: Karrer, Cecile, Roiss, Thomas, von Goetz, Natalie, Gramec Skledar, Darja, Peterlin Mašič, Lucija, Hungerbühler, Konrad
Formato: Artigo
Idioma:Inglês
Publicado: Environmental Health Perspectives 2018
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6108829/
https://ncbi.nlm.nih.gov/pubmed/29995627
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1289/EHP2739
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