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Parathyroid hormone regulates 25-hydroxyvitamin D(3)-24-hydroxylase mRNA by altering its stability

The up-regulation of the 25-hydroxyvitamin D(3)-24-hydroxylase by 1,25-dihydroxyvitamin D(3) [1,25(OH)(2)D(3)] is well established and occurs at the transcriptional level through two vitamin D response elements in the promoter of the gene. However, the mechanism of down-regulation of the 24-hydroxyl...

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Détails bibliographiques
Auteurs principaux: Zierold, Claudia, Mings, Jamie A., DeLuca, Hector F.
Format: Artigo
Langue:Inglês
Publié: The National Academy of Sciences 2001
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC61082/
https://ncbi.nlm.nih.gov/pubmed/11698670
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.241516798
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