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Translating anti-CD19 CAR T-cell therapy into clinical practice for relapsed/refractory diffuse large B-cell lymphoma

Chimeric antigen receptor T cells demonstrate efficacy in B-cell malignancies, leading to US Food and Drug Administration approval of axicabtagene ciloleucel (October 2017) and tisagenlecleucel (May 2018) for large B-cell lymphomas after 2 prior lines of therapy. Durable remissions are seen in 30% t...

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Bibliografiske detaljer
Udgivet i:Blood
Main Authors: Chow, Victor A., Shadman, Mazyar, Gopal, Ajay K.
Format: Artigo
Sprog:Inglês
Udgivet: American Society of Hematology 2018
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6107879/
https://ncbi.nlm.nih.gov/pubmed/29914976
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2018-04-839217
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