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Polyubiquitination inhibition of estrogen receptor alpha and its implications in breast cancer
Estrogen receptor alpha (ERα) is detected in more than 70% of the cases of breast cancer. Nuclear activity of ERα, a transcriptional regulator, is linked to the development of mammary tumors, whereas the extranuclear activity of ERα is related to endocrine therapy resistance. ERα polyubiquitination...
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| Publicado no: | World J Clin Oncol |
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| Main Authors: | , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Baishideng Publishing Group Inc
2018
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6107474/ https://ncbi.nlm.nih.gov/pubmed/30148069 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.5306/wjco.v9.i4.60 |
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