Ventral CA3 Activation Mediates Prophylactic Ketamine Efficacy Against Stress-Induced Depressive-Like Behavior

BACKGROUND: We previously reported that a single injection of ketamine prior to stress protects against the onset of depressive-like behavior and attenuates learned fear. However, the molecular pathways and brain circuits underlying ketamine-induced stress resilience are still largely unknown. METHO...

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Veröffentlicht in:Biol Psychiatry
Hauptverfasser: Mastrodonato, Alessia, Martinez, Randy, Pavlova, Ina P., LaGamma, Christina T., Brachman, Rebecca A., Robison, Alfred J., Denny, Christine A.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2018
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6107435/
https://ncbi.nlm.nih.gov/pubmed/29615190
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.biopsych.2018.02.011
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