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The 2.0-Å crystal structure of tachylectin 5A provides evidence for the common origin of the innate immunity and the blood coagulation systems

Because invertebrates lack an adaptive immune system, they had to evolve effective intrinsic defense strategies against a variety of microbial pathogens. This ancient form of host defense, the innate immunity, is present in all multicellular organisms including humans. The innate immune system of th...

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Udgivet i:Proc Natl Acad Sci U S A
Principais autores: Kairies, Norman, Beisel, Hans-Georg, Fuentes-Prior, Pablo, Tsuda, Ryoko, Muta, Tatsushi, Iwanaga, Sadaaki, Bode, Wolfram, Huber, Robert, Kawabata, Shun-ichiro
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 2001
Fag:
Biological Sciences
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC61073/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11707569/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.201523798
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