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ARID1A-deficiency in urothelial bladder cancer: No predictive biomarker for EZH2-inhibitor treatment response?

Bladder cancer therapy relies on aggressive treatments highlighting the need for new, targeted therapies with reduced side effects. SWI/SNF complexes are mutated in ~20% across human cancers and dependency of SWI/SNF-deficient tumors on EZH2 has been uncovered recently. To systematically dissect the...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Julkaisussa:PLoS One
Päätekijät: Garczyk, Stefan, Schneider, Ursula, Lurje, Isabella, Becker, Katharina, Vögeli, Thomas A., Gaisa, Nadine T., Knüchel, Ruth
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Public Library of Science 2018
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC6107234/
https://ncbi.nlm.nih.gov/pubmed/30138427
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0202965
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