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Toll-Like Receptor Evolution in Birds: Gene Duplication, Pseudogenization, and Diversifying Selection

Toll-like receptors (TLRs) are key sensor molecules in vertebrates triggering initial phases of immune responses to pathogens. The avian TLR family typically consists of ten receptors, each adapted to distinct ligands. To understand the complex evolutionary history of each avian TLR, we analyzed all...

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Detalhes bibliográficos
Publicado no:Mol Biol Evol
Main Authors: Velová, Hana, Gutowska-Ding, Maria W, Burt, David W, Vinkler, Michal
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6107061/
https://ncbi.nlm.nih.gov/pubmed/29893911
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/molbev/msy119
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