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Perioperative use of cefazolin ameliorates postoperative cognitive dysfunction but induces gut inflammation in mice

BACKGROUND: Emerging evidence indicates that long-time use of multiple antibiotics can induce cognitive dysfunction via gut dysbiosis. Cefazolin is often used for 3 to 5 days to prevent perioperative infection. This study is to detect the impact of perioperative use of cefazolin on inflammatory resp...

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Détails bibliographiques
Publié dans:J Neuroinflammation
Auteurs principaux: Liang, Peng, Shan, Weiran, Zuo, Zhiyi
Format: Artigo
Langue:Inglês
Publié: BioMed Central 2018
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6106929/
https://ncbi.nlm.nih.gov/pubmed/30134985
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12974-018-1274-6
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