Misidentification of runs of homozygosity islands in cattle caused by interference with copy number variation or large intermarker distances

BACKGROUND: Runs of homozygosity (ROH) islands are stretches of homozygous sequence in the genome of a large proportion of individuals in a population. Algorithms for the detection of ROH depend on the similarity of haplotypes. Coverage gaps and copy number variants (CNV) may result in incorrect ide...

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Bibliografski detalji
Izdano u:Genet Sel Evol
Glavni autori: Nandolo, Wilson, Utsunomiya, Yuri T., Mészáros, Gábor, Wurzinger, Maria, Khayadzadeh, Negar, Torrecilha, Rafaela B. P., Mulindwa, Henry A., Gondwe, Timothy N., Waldmann, Patrik, Ferenčaković, Maja, Garcia, José F., Rosen, Benjamin D., Bickhart, Derek, van Tassell, Curt P., Curik, Ino, Sölkner, Johann
Format: Artigo
Jezik:Inglês
Izdano: BioMed Central 2018
Teme:
Research Article
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6106898/
https://ncbi.nlm.nih.gov/pubmed/30134820
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12711-018-0414-x
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