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Models of cell signaling uncover molecular mechanisms of high-risk neuroblastoma and predict disease outcome

BACKGROUND: Despite the progress in neuroblastoma therapies the mortality of high-risk patients is still high (40–50%) and the molecular basis of the disease remains poorly known. Recently, a mathematical model was used to demonstrate that the network regulating stress signaling by the c-Jun N-termi...

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Detalhes bibliográficos
Publicado no:Biol Direct
Main Authors: Hidalgo, Marta R., Amadoz, Alicia, Çubuk, Cankut, Carbonell-Caballero, José, Dopazo, Joaquín
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2018
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6106876/
https://ncbi.nlm.nih.gov/pubmed/30134948
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13062-018-0219-4
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