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TRPV4 ion channel is a novel regulator of dermal myofibroblast differentiation

Scleroderma is a multisystem fibroproliferative disease with no effective medical treatment. Myofibroblasts are critical to the fibrogenic tissue repair process in the skin and many internal organs. Emerging data support a role for both matrix stiffness, and transforming growth factor β1 (TGFβ1), in...

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Bibliografiske detaljer
Udgivet i:Am J Physiol Cell Physiol
Main Authors: Sharma, Shweta, Goswami, Rishov, Merth, Michael, Cohen, Jonathan, Lei, Kai Y., Zhang, David X., Rahaman, Shaik O.
Format: Artigo
Sprog:Inglês
Udgivet: American Physiological Society 2017
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6105932/
https://ncbi.nlm.nih.gov/pubmed/28249987
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpcell.00187.2016
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