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Conjugated Bile Acids Promote Invasive Growth of Esophageal Adenocarcinoma Cells and Cancer Stem Cell Expansion via Sphingosine 1-Phosphate Receptor 2–Mediated Yes-Associated Protein Activation

Esophageal adenocarcinoma (EAC) is the sixth leading cause of cancer deaths worldwide and has been dramatically increasing in incidence over the past decade. Gastroesophageal reflux and Barrett esophagus are well-established risk factors for disease progression. Conjugated bile acids (CBAs), includi...

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Bibliografische gegevens
Gepubliceerd in:Am J Pathol
Hoofdauteurs: Liu, Runping, Li, Xiaojiaoyang, Hylemon, Phillip B., Zhou, Huiping
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: American Society for Investigative Pathology 2018
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6105923/
https://ncbi.nlm.nih.gov/pubmed/29963993
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ajpath.2018.05.015
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