Bioengineering of bacterial pathogens for noninvasive imaging and in vivo evaluation of therapeutics

Critical bacterial pathogens of public health and biodefense concerns were engineered to constitutively express Escherichia coli enzyme thymidine kinase (TK) that allows for noninvasive nuclear imaging via phosphorylation and entrapment of radiolabeled nucleoside analog 1-(2′deoxy-2′-fluoro-β-D-arab...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Julkaisussa:Sci Rep
Päätekijät: Rajamani, Sathish, Kuszpit, Kyle, Scarff, Jennifer M., Lundh, Linnea, Khan, Maisha, Brown, Jennifer, Stafford, Robert, Cazares, Lisa H., Panchal, Rekha G., Bocan, Thomas
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Nature Publishing Group UK 2018
Aiheet:
Article
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC6105664/
https://ncbi.nlm.nih.gov/pubmed/30135466
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-30806-x
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