Early cellular innate immune responses drive Zika viral persistence and tissue tropism in pigtail macaques

The immunological and virological events that contribute to the establishment of Zika virus (ZIKV) infection in humans are unclear. Here, we show that robust cellular innate immune responses arising early in the blood and tissues in response to ZIKV infection are significantly stronger in males and...

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Dades bibliogràfiques
Publicat a:Nat Commun
Autors principals: O’Connor, Megan A., Tisoncik-Go, Jennifer, Lewis, Thomas B., Miller, Charlene J., Bratt, Debra, Moats, Cassie R., Edlefsen, Paul T., Smedley, Jeremy, Klatt, Nichole R., Gale, Michael, Fuller, Deborah Heydenburg
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group UK 2018
Matèries:
Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6105614/
https://ncbi.nlm.nih.gov/pubmed/30135445
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-018-05826-w
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