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Mitoprotective Therapy Preserves Chondrocyte Viability and Prevents Cartilage Degeneration in an Ex Vivo Model of Posttraumatic Osteoarthritis

No disease-modifying osteoarthritis (OA) drugs are available to prevent posttraumatic osteoarthritis (PTOA). Mitochondria (MT) mediate the pathogenesis of many degenerative diseases, and recent evidence indicates that MT dysfunction is a peracute (within minutes to hours) response of cartilage to me...

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Bibliografski detalji
Izdano u:J Orthop Res
Glavni autori: Delco, Michelle L., Bonnevie, Edward D., Szeto, Hazel S., Bonassar, Lawrence J., Fortier, Lisa A.
Format: Artigo
Jezik:Inglês
Izdano: 2018
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6105558/
https://ncbi.nlm.nih.gov/pubmed/29469223
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jor.23882
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