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Elevated free hemoglobin and decreased haptoglobin levels are associated with adverse clinical outcomes, unfavorable physiologic measures and altered inflammatory markers in pediatric cardiac surgery patients
BACKGROUND: There are clinical, mechanistic and animal model data suggesting that free hemoglobin, heme and iron may contribute to infection, thrombosis, multi-organ failure and death in critically ill patients. These outcomes may be mitigated by hemoglobin binding proteins such as haptoglobin. METH...
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| Pubblicato in: | Transfusion |
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| Autori principali: | , , , , , , , , , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
2018
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6105435/ https://ncbi.nlm.nih.gov/pubmed/29603246 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/trf.14601 |
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