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Metformin activates duodenal AMPK and a neuronal network to lower glucose production
Metformin is a first-line therapeutic option for the treatment of hyperglycemia in type 2 diabetes, despite its underlying regulatory mechanisms remaining relatively unknown. Metformin lowers blood glucose levels by inhibiting hepatic glucose production (GP), originally postulated to be resultant fr...
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| Udgivet i: | Nat Med |
|---|---|
| Main Authors: | , , , , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2015
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6104807/ https://ncbi.nlm.nih.gov/pubmed/25849133 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nm.3787 |
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