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Constitutively Active MDA5 Proteins Are Inhibited by Paramyxovirus V Proteins

Excessive interferon (IFN) production and signaling can lead to immunological and developmental defects giving rise to autoimmune diseases referred to collectively as “type I interferonopathies.” A subset of these diseases is caused by monogenic mutations affecting proteins involved in nucleic acid...

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Detalles Bibliográficos
Publicado en:J Interferon Cytokine Res
Main Authors: Mandhana, Roli, Qian, Lily K., Horvath, Curt M.
Formato: Artigo
Idioma:Inglês
Publicado: Mary Ann Liebert, Inc. 2018
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6104658/
https://ncbi.nlm.nih.gov/pubmed/30130154
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/jir.2018.0049
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