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Intracellular emetic signaling evoked by the L-type Ca(2+) channel agonist FPL64176 in the least shrew (Cryptotis parva)

Ca(2+) plays a major role in maintaining cellular homeostasis and regulates processes including apoptotic cell death and side-effects of cancer chemotherapy including vomiting. Currently we explored the emetic mechanisms of FPL64176, an L-type Ca(2+) channel (LTCC) agonist with maximal emetogenic ef...

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Detalhes bibliográficos
Publicado no:Eur J Pharmacol
Main Authors: Zhong, Weixia, Chebolu, Seetha, Darmani, Nissar A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6104632/
https://ncbi.nlm.nih.gov/pubmed/29966616
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ejphar.2018.06.035
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