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Pharmacovigilance Evaluation of the Association Between DPP-4 Inhibitors and Heart Failure: Stimulated Reporting and Moderation by Drug Interactions

INTRODUCTION: In the SAVOR-TIMI trial, the risk of heart failure (HF) was increased by 27% in T2D patients randomized to the dipeptidyl peptidase-4 inhibitor (DPP4i) saxagliptin. Other studies have provided inconsistent results regarding this association. Herein, we performed a pharmacovigilance ana...

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Detalhes bibliográficos
Publicado no:Diabetes Ther
Main Authors: Fadini, Gian Paolo, Sarangdhar, Mayur, Avogaro, Angelo
Formato: Artigo
Idioma:Inglês
Publicado em: Springer Healthcare 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6104265/
https://ncbi.nlm.nih.gov/pubmed/29549573
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s13300-018-0408-2
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