Connexin 43 Hemichannel Activity Promoted by Pro-Inflammatory Cytokines and High Glucose Alters Endothelial Cell Function

The present work was done to elucidate whether hemichannels of a cell line derived from endothelial cells are affected by pro-inflammatory conditions (high glucose and IL-1β/TNF-α) known to lead to vascular dysfunction. We used EAhy 926 cells treated with high glucose and IL-1β/TNF-α. The hemichanne...

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Detalles Bibliográficos
Publicado en:Front Immunol
Main Authors: Sáez, Juan C., Contreras-Duarte, Susana, Gómez, Gonzalo I., Labra, Valeria C., Santibañez, Cristian A., Gajardo-Gómez, Rosario, Avendaño, Beatriz C., Díaz, Esteban F., Montero, Trinidad D., Velarde, Victoria, Orellana, Juan A.
Formato: Artigo
Idioma:Inglês
Publicado: Frontiers Media S.A. 2018
Assuntos:
Immunology
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6104120/
https://ncbi.nlm.nih.gov/pubmed/30158937
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2018.01899
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