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Mutations causing low level antibiotic resistance ensure bacterial survival in antibiotic-treated hosts
In 474 genome sequenced Pseudomonas aeruginosa isolates from 34 cystic fibrosis (CF) patients, 40% of these harbor mutations in the mexZ gene encoding a negative regulator of the MexXY-OprM efflux pump associated with aminoglycoside and fluoroquinolone resistance. Surprisingly, resistance to aminogl...
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| Publicado en: | Sci Rep |
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| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
Nature Publishing Group UK
2018
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6104031/ https://ncbi.nlm.nih.gov/pubmed/30131514 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-30972-y |
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