Forward and reverse mutations in stages of cancer development

BACKGROUND: Massive occurrences of interstitial loss of heterozygosity (LOH) likely resulting from gene conversions were found by us in different cancers as a type of single-nucleotide variations (SNVs), comparable in abundance to the commonly investigated gain of heterozygosity (GOH) type of SNVs,...

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Pubblicato in:Hum Genomics
Autori principali: Hu, Taobo, Kumar, Yogesh, Shazia, Iram, Duan, Shen-Jia, Li, Yi, Chen, Lei, Chen, Jin-Fei, Yin, Rong, Kwong, Ava, Leung, Gilberto Ka-Kit, Mat, Wai-Kin, Wu, Zhenggang, Long, Xi, Chan, Cheuk-Hin, Chen, Si, Lee, Peggy, Ng, Siu-Kin, Ho, Timothy Y. C., Yang, Jianfeng, Ding, Xiaofan, Tsang, Shui-Ying, Zhou, Xuqing, Zhang, Dan-Hua, Zhou, En-Xiang, Xu, Lin, Poon, Wai-Sang, Wang, Hong-Yang, Xue, Hong
Natura: Artigo
Lingua:Inglês
Pubblicazione: BioMed Central 2018
Soggetti:
Primary Research
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6104001/
https://ncbi.nlm.nih.gov/pubmed/30134973
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s40246-018-0170-6
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