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Proteomic characterization of endogenous substrates of mammalian ubiquitin ligase Hrd1
BACKGROUND: Endoplasmic reticulum (ER)-associated degradation (ERAD) regulates protein homeostasis in the secretory pathway by targeting misfolded or unassembled proteins for degradation by the proteasome. Hrd1 is a conserved multi-spanning membrane bound ubiquitin ligase required for ubiquitination...
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| Publicado no: | Cell Biosci |
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| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
BioMed Central
2018
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6103995/ https://ncbi.nlm.nih.gov/pubmed/30167107 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13578-018-0245-z |
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