Influence of sample collection tube method, anticoagulant-containing plasma versus serum, on influenza virus hemagglutination inhibition titer and microneutralization titer serological assays

BACKGROUND: The hemagglutination-inhibition (HAI) assay is a critical component for measurement of immunogenicity in influenza vaccine development. It is unknown if the results can be influenced by sample type and anticoagulants. The purpose of this study was to evaluate the influence of different s...

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Publicado en:BMC Health Serv Res
Autores principales: Morrison, Brian J., Martin, Nicholas J., Rehman, Tauseef, Ewing, Dan, Dewar, Robin L., Metcalf, Julia, Sun, Peifang, Beigel, John, Luke, Thomas C., Raviprakash, Kanakatte
Formato: Artigo
Lenguaje:Inglês
Publicado: BioMed Central 2018
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Research Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC6103864/
https://ncbi.nlm.nih.gov/pubmed/30134892
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12913-018-3465-3
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