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Small RNAs gained during epididymal transit of sperm are essential for embryonic development in mice

The small RNA payload of mammalian sperm undergoes dramatic remodeling during development, as several waves of microRNAs and tRNA fragments are shipped to sperm during post-testicular maturation in the epididymis. Here, we take advantage of this developmental process to probe the function of the spe...

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Bibliographic Details
Published in:Dev Cell
Main Authors: Conine, Colin C., Sun, Fengyun, Song, Lina, Rivera-Pérez, Jaime A., Rando, Oliver J.
Format: Artigo
Language:Inglês
Published: 2018
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6103825/
https://ncbi.nlm.nih.gov/pubmed/30057276
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.devcel.2018.06.024
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