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Estrogenic-dependent glutamatergic neurotransmission from kisspeptin neurons governs feeding circuits in females

The neuropeptides tachykinin2 (Tac2) and kisspeptin (Kiss1) in hypothalamic arcuate nucleus Kiss1 (Kiss1(ARH)) neurons are essential for pulsatile release of GnRH and reproduction. Since 17β-estradiol (E2) decreases Kiss1 and Tac2 mRNA expression in Kiss1(ARH) neurons, the role of Kiss1(ARH) neurons...

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Detalhes bibliográficos
Publicado no:eLife
Main Authors: Qiu, Jian, Rivera, Heidi M, Bosch, Martha A, Padilla, Stephanie L, Stincic, Todd L, Palmiter, Richard D, Kelly, Martin J, Rønnekleiv, Oline K
Formato: Artigo
Idioma:Inglês
Publicado em: eLife Sciences Publications, Ltd 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6103748/
https://ncbi.nlm.nih.gov/pubmed/30079889
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.35656
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