Carbon nanotubes, but not spherical nanoparticles, block autophagy by a shape-related targeting of lysosomes in murine macrophages

Nanoparticles (NPs) can be toxic, depending on their physico-chemical characteristics. Macroautophagy/autophagy could represent a potential underlying mechanism of this toxicity. We therefore set up a study aimed to characterize in depth the effects, on autophagy, of macrophage exposure to NPs, with...

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Dettagli Bibliografici
Pubblicato in:Autophagy
Autori principali: Cohignac, Vanessa, Landry, Marion Julie, Ridoux, Audrey, Pinault, Mathieu, Annangi, Balasubramanyam, Gerdil, Adèle, Herlin-Boime, Nathalie, Mayne, Martine, Haruta, Masatake, Codogno, Patrice, Boczkowski, Jorge, Pairon, Jean-Claude, Lanone, Sophie
Natura: Artigo
Lingua:Inglês
Pubblicazione: Taylor & Francis 2018
Soggetti:
Brief Report - Basic Science
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6103705/
https://ncbi.nlm.nih.gov/pubmed/29938576
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/15548627.2018.1474993
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