Cryptic exon splicing function of TARDBP interacts with autophagy in nervous tissue

TARDBP (TAR DNA binding protein) is one of the components of neuronal aggregates in sporadic amyotrophic lateral sclerosis (ALS) and frontotemporal lobar degeneration. We have developed a simple quantitative method to evaluate TARDBP splicing function that was applied to spinal cord, brainstem, moto...

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Salvato in:
Dettagli Bibliografici
Pubblicato in:Autophagy
Autori principali: Torres, Pascual, Ramírez-Núñez, Omar, Romero-Guevara, Ricardo, Barés, Gisel, Granado-Serrano, Ana B., Ayala, Victòria, Boada, Jordi, Fontdevila, Laia, Povedano, Monica, Sanchís, Daniel, Pamplona, Reinald, Ferrer, Isidro, Portero-Otín, Manuel
Natura: Artigo
Lingua:Inglês
Pubblicazione: Taylor & Francis 2018
Soggetti:
Brief Report - Basic Science
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6103657/
https://ncbi.nlm.nih.gov/pubmed/29912613
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/15548627.2018.1474311
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